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On the value of Mendelian laws of segregation in families: data quality control, imputation and beyond

When analyzing family data, we dream of perfectly informative data, even whole genome sequences (WGS) for all family members. Reality intervenes, and we find next-generation sequence (NGS) data have error, and are often too expensive or impossible to collect on everyone. Genetic Analysis Workshop 18...

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Hlavní autoři: Blue, Elizabeth Marchani, Sun, Lei, Tintle, Nathan L., Wijsman, Ellen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135526/
https://ncbi.nlm.nih.gov/pubmed/25112184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21821
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