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An essential role for caspase-1 in the induction of murine lupus and its associated vascular damage

OBJECTIVE: Systemic Lupus Erythematosus (SLE) is a systemic autoimmune syndrome associated with organ damage and an elevated risk of cardiovascular disease (CVD) resulting from activation of both innate and adaptive immune pathways. Recently, increased activation of the inflammasome machinery in SLE...

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Detalhes bibliográficos
Main Authors: Kahlenberg, J. Michelle, Yalavarthi, Srilakshmi, Zhao, Wenpu, Hodgin, Jeffrey B., Reed, Tamra J., Tsuji, Noriko M., Kaplan, Mariana J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135431/
https://ncbi.nlm.nih.gov/pubmed/24449582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38225
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