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Analysis of rare variant population structure in Europeans explains differential stratification of gene-based tests
There is substantial interest in the role of rare genetic variants in the etiology of complex human diseases. Several gene-based tests have been developed to simultaneously analyze multiple rare variants for association with phenotypic traits. The tests can largely be partitioned into two classes –...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135410/ https://ncbi.nlm.nih.gov/pubmed/24398795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.297 |
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