Sequence-specific DNA binding by p53: identification of target sites and lack of binding to p53 - MDM2 complexes.

An immune selection procedure was employed in order to isolate p53 binding sites from mouse genomic DNA. Two DNA clones capable of tight specific interaction with wild type p53 were subjected to further characterization. In both cases, the p53 binding regions displayed a high degree of sequence homo...

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Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: Zauberman, A, Barak, Y, Ragimov, N, Levy, N, Oren, M
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413530/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8334996/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05941.x
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