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A functional p53-responsive intronic promoter is contained within the human mdm2 gene.
The mdm2 gene is a target for transcriptional activation by the p53 tumor suppressor gene product. Previous work has revealed that the mouse mdm2 gene contains two promoters: one is located upstream to the gene and is active in the absence of p53, the other resides within the first intron and requir...
Uloženo v:
| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
1995
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307078/ https://ncbi.nlm.nih.gov/pubmed/7651818 |
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