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A functional p53-responsive intronic promoter is contained within the human mdm2 gene.
The mdm2 gene is a target for transcriptional activation by the p53 tumor suppressor gene product. Previous work has revealed that the mouse mdm2 gene contains two promoters: one is located upstream to the gene and is active in the absence of p53, the other resides within the first intron and requir...
Tallennettuna:
| Julkaisussa: | Nucleic Acids Res |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
1995
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| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307078/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7651818/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.14.2584 |
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