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A functional p53-responsive intronic promoter is contained within the human mdm2 gene.

The mdm2 gene is a target for transcriptional activation by the p53 tumor suppressor gene product. Previous work has revealed that the mouse mdm2 gene contains two promoters: one is located upstream to the gene and is active in the absence of p53, the other resides within the first intron and requir...

詳細記述

保存先:
書誌詳細
主要な著者: Zauberman, A, Flusberg, D, Haupt, Y, Barak, Y, Oren, M
フォーマット: Artigo
言語:Inglês
出版事項: 1995
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC307078/
https://ncbi.nlm.nih.gov/pubmed/7651818
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