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Autophagy dysregulation in cell culture and animals models of Spinal Muscular Atrophy
Abnormal autophagy has become a central thread linking neurodegenerative diseases, particularly of the motor neuron. One such disease is spinal muscular atrophy (SMA), a genetic neuromuscular disorder caused by mutations in the SMN1 gene resulting in low levels of Survival Motor Neuron (SMN) protein...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135029/ https://ncbi.nlm.nih.gov/pubmed/24983518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2014.06.006 |
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