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Vitamin D3 supplementation increases fibroblast growth factor-23 in HIV-infected youth treated with tenofovir disoproxil fumarate

BACKGROUND: Tenofovir (TDF) is associated with phosphaturia and elevated 1,25 dihydroxy vitamin D (1,25-OH(2)D). Fibroblast growth factor 23 (FGF23) causes phosphaturia and increases in response to elevated 1,25-OH(2)D. Vitamin D binding protein (VDBP) binds to 1,25-OH(2)D, decreasing its biologic a...

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Bibliografiske detaljer
Main Authors: Havens, Peter L, Hazra, Rohan, Stephensen, Charles B, Kiser, Jennifer J, Flynn, Patricia M, Wilson, Craig M, Rutledge, Brandy, Bethel, James, Pan, Cynthia G, Woodhouse, Leslie R, Van Loan, Marta D, Liu, Nancy, Lujan-Zilbermann, Jorge, Baker, Alyne, Kapogiannis, Bill G, Gordon, Catherine M, Mulligan, Kathleen
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135028/
https://ncbi.nlm.nih.gov/pubmed/24535626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP2755
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