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Vitamin D3 supplementation increases fibroblast growth factor-23 in HIV-infected youth treated with tenofovir disoproxil fumarate

BACKGROUND: Tenofovir (TDF) is associated with phosphaturia and elevated 1,25 dihydroxy vitamin D (1,25-OH(2)D). Fibroblast growth factor 23 (FGF23) causes phosphaturia and increases in response to elevated 1,25-OH(2)D. Vitamin D binding protein (VDBP) binds to 1,25-OH(2)D, decreasing its biologic a...

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Detalhes bibliográficos
Main Authors: Havens, Peter L, Hazra, Rohan, Stephensen, Charles B, Kiser, Jennifer J, Flynn, Patricia M, Wilson, Craig M, Rutledge, Brandy, Bethel, James, Pan, Cynthia G, Woodhouse, Leslie R, Van Loan, Marta D, Liu, Nancy, Lujan-Zilbermann, Jorge, Baker, Alyne, Kapogiannis, Bill G, Gordon, Catherine M, Mulligan, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135028/
https://ncbi.nlm.nih.gov/pubmed/24535626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP2755
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