Decline in Bone Mass With Tenofovir Disoproxil Fumarate/Emtricitabine Is Associated With Hormonal Changes in the Absence of Renal Impairment When Used by HIV-Uninfected Adolescent Boys and Young Men for HIV Preexposure Prophylaxis

BACKGROUND. We aimed to define the relative importance of renal and endocrine changes in tenofovir disoproxil fumarate (TDF)–related bone toxicity. METHODS. In a study of daily TDF/emtricitabine (FTC) preexposure prophylaxis (PrEP) in human immunodeficiency virus (HIV)–uninfected young men who have...

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Veröffentlicht in:Clin Infect Dis
Hauptverfasser: Havens, Peter L., Stephensen, Charles B., Van Loan, Marta D., Schuster, Gertrud U., Woodhouse, Leslie R., Flynn, Patricia M., Gordon, Catherine M., Pan, Cynthia G., Rutledge, Brandy, Liu, Nancy, Wilson, Craig M., Hazra, Rohan, Hosek, Sybil G., Anderson, Peter L., Seifert, Sharon M., Kapogiannis, Bill G., Mulligan, Kathleen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Major Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366053/
https://ncbi.nlm.nih.gov/pubmed/28013265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciw765
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