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Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas.

E-Cadherin, a cell adhesion molecule, which plays a key role in maintaining the epithelial phenotype, is regarded as an invasion-suppressor gene in light of accumulating evidence from in vitro experiments and clinical observations. In an attempt to clarify the mechanism responsible for inactivation...

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Main Authors: Yoshiura, K, Kanai, Y, Ochiai, A, Shimoyama, Y, Sugimura, T, Hirohashi, S
Formato: Artigo
Idioma:Inglês
Publicado: 1995
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC41350/
https://ncbi.nlm.nih.gov/pubmed/7543680
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