Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas.
E-Cadherin, a cell adhesion molecule, which plays a key role in maintaining the epithelial phenotype, is regarded as an invasion-suppressor gene in light of accumulating evidence from in vitro experiments and clinical observations. In an attempt to clarify the mechanism responsible for inactivation...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41350/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7543680/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.16.7416 |
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