A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development.
The Ca(2+)-dependent cell adhesion molecule E-cadherin functions in the establishment and maintenance of epithelial cell morphology during embryogenesis and adulthood. Downregulation or complete shut-down of E-cadherin expression and mutation of the gene are observed during the progression of tumors...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42719/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7846066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.3.855 |
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