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A C-14 labeled Py-Im polyamide localizes to a subcutaneous prostate cancer tumor

In an effort to quantitate Py-Im polyamide concentrations in vivo, we synthesized the C-14 radioactively labeled compounds 1-3, and investigated their tumor localization in a subcutaneous xenograft model of prostate cancer (LNCaP). Tumor concentrations were compared with representative host tissues,...

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Detalhes bibliográficos
Main Authors: Raskatov, Jevgenij A., Puckett, James W., Dervan, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134956/
https://ncbi.nlm.nih.gov/pubmed/24780272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.04.010
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