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β-catenin activation in a novel liver progenitor cell type is sufficient to cause hepatocellular carcinoma and hepatoblastoma

Hepatocellular carcinoma (HCC) was thought historically to arise from hepatocytes, but gene expression studies have suggested it can also arise from fetal progenitor cells or their adult progenitor progeny. Here we report the identification of a unique population of fetal liver progenitor cells in m...

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Hlavní autoři: Mokkapati, Sharada, Niopek, Katharina, Huang, Le, Cunniff, Kegan J., Ruteshouser, E. Cristy, deCaestecker, Mark, Finegold, Milton J., Huff, Vicki
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134699/
https://ncbi.nlm.nih.gov/pubmed/24848510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3275
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