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Heparanase co-operates with Ras to drive breast and skin tumorigenesis
Heparanase has been implicated in cancer but its contribution to the early stages of cancer development is uncertain. In this study, we utilized non-transformed human MCF10A mammary epithelial cells and two genetic mouse models (Hpa-transgenic and knockout mice) to explore heparanase function at ear...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4134691/ https://ncbi.nlm.nih.gov/pubmed/24970482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2962 |
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