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Human Papillomavirus E7 oncoprotein transgenic skin develops an enhanced inflammatory response to 2,4-Dinitrochlorobenzene by an arginase-1 dependent mechanism
We have shown that expression of Human Papillomavirus type 16 E7 (HPV16.E7) protein within epithelial cells, as occurs in HPV associated-premalignancy and cancers, results in local immune suppression, and a weak and ineffective immune response to E7 protein. However, a robust acute inflammatory stim...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4134683/ https://ncbi.nlm.nih.gov/pubmed/24732401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.186 |
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