Human Papillomavirus E7 oncoprotein transgenic skin develops an enhanced inflammatory response to 2,4-Dinitrochlorobenzene by an arginase-1 dependent mechanism

We have shown that expression of Human Papillomavirus type 16 E7 (HPV16.E7) protein within epithelial cells, as occurs in HPV associated-premalignancy and cancers, results in local immune suppression, and a weak and ineffective immune response to E7 protein. However, a robust acute inflammatory stim...

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Detalhes bibliográficos
Main Authors: Tran, L.S., Bergot, A-S., Mattarollo, S.R., Mittal, D., Frazer, I.H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134683/
https://ncbi.nlm.nih.gov/pubmed/24732401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.186
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