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The Role of Mass Transport Limitation and Surface Heterogeneity in the Biophysical Characterization of Macromolecular Binding Processes by SPR Biosensing

This chapter presents an introduction to the kinetic analysis of SPR biosensor data for the determination of affinity and kinetic rate constants of biomolecular interactions between an immobilized and a soluble binding partner. The need to be aware of and critically tests the assumptions underlying...

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Autors principals: Schuck, Peter, Zhao, Huaying
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134667/
https://ncbi.nlm.nih.gov/pubmed/20217612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60761-670-2_2
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