Phosphorylated protein phosphatase 2A determines poor outcome in patients with metastatic colorectal cancer

BACKGROUND: Protein phosphatase 2A (PP2A) is a tumour suppressor frequently inactivated in human cancer and its tyrosine-307 phosphorylation has been reported as a molecular inhibitory mechanism. METHODS: Expression of phosphorylated PP2A (p-PP2A) was evaluated in 250 metastatic colorectal cancer (C...

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Autores principales: Cristóbal, I, Manso, R, Rincón, R, Caramés, C, Zazo, S, del Pulgar, T G, Cebrián, A, Madoz-Gúrpide, J, Rojo, F, García-Foncillas, J
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134505/
https://ncbi.nlm.nih.gov/pubmed/25003662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.376
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