Downregulation of microRNA-199b predicts unfavorable prognosis and emerges as a novel therapeutic target which contributes to PP2A inhibition in metastatic colorectal cancer

The tumor suppressor microRNA-199b (miR-199b) is a negative SET regulator associated with poor outcome in some human cancers. However, its expression levels as well as potential biological and clinical significance in colorectal cancer (CRC) remain completely unexplored. The PP2A inhibitor SET has s...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cristóbal, Ion, Caramés, Cristina, Rincón, Raúl, Manso, Rebeca, Madoz-Gúrpide, Juan, Torrejón, Blanca, González-Alonso, Paula, Rojo, Federico, García-Foncillas, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522310/
https://ncbi.nlm.nih.gov/pubmed/27517624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11174
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