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Soluble biglycan induces the production of ICAM-1 and MCP-1 in human aortic valve interstitial cells through TLR2/4 and the ERK1/2 pathway

OBJECTIVE: Mononuclear cell infiltration in valvular tissue is one of the characteristics in calcific aortic valve disease. The inflammatory responses of aortic valve interstitial cells (AVICs) play an important role in valvular inflammation. However, it remains unclear what may evoke AVIC inflammat...

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Sonraí Bibleagrafaíochta
Main Authors: Song, Rui, Ao, Lihua, Zhao, Ke-seng, Zheng, Daniel, Venardos, Neil, Fullerton, David A., Meng, Xianzhong
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134418/
https://ncbi.nlm.nih.gov/pubmed/24875140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-014-0743-3
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