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Minocycline and Doxycycline, but not Tetracycline, Mitigate Liver and Kidney Injury after Hemorrhagic Shock/Resuscitation

BACKGROUND: Despite recovery of hemodynamics by fluid resuscitation after hemorrhage, development of the systemic inflammatory response and multiple organ dysfunction syndromes can nonetheless lead to death. Minocycline and doxycycline are tetracycline derivatives that are protective in models of hy...

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Auteurs principaux: Kholmukhamedov, Andaleb, Czerny, Christoph, Hu, Jiangting, Schwartz, Justin, Zhong, Zhi, Lemasters, John J.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134396/
https://ncbi.nlm.nih.gov/pubmed/24978888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000213
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