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An Engineered Factor Va Prevents Bleeding Induced by Anticoagulant wt Activated Protein C

OBJECTIVE: An increased risk of bleeding is observed in patients receiving activated protein C (APC), which may be a limiting factor for the application of novel APC therapies. Since APC's therapeutic effects often require its cytoprotective activities on cells but not APC's anticoagulant...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: von Drygalski, Annette, Bhat, Vikas, Gale, Andrew J., Burnier, Laurent, Cramer, Thomas J., Griffin, John H., Mosnier, Laurent O.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134195/
https://ncbi.nlm.nih.gov/pubmed/25127130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104304
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