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Dysregulation of the Axonal Trafficking of Nuclear-encoded Mitochondrial mRNA alters Neuronal Mitochondrial Activity and Mouse Behavior

Local translation of nuclear-encoded mitochondrial mRNAs is essential for mitochondrial activity, yet there is little insight into the role that axonal trafficking of these transcripts play in neuronal function and behavior. Previously, we identified a 38 nucleotide stem-loop structure (zipcode) in...

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Hlavní autoři: Kar, Amar N., Sun, Ching-Yu, Reichard, Kathryn, Gervasi, Noreen M., Pickel, James, Nakazawa, Kazu, Gioio, Anthony E., Kaplan, Barry B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133933/
https://ncbi.nlm.nih.gov/pubmed/24151253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.22141
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