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Dysregulation of the Axonal Trafficking of Nuclear-encoded Mitochondrial mRNA alters Neuronal Mitochondrial Activity and Mouse Behavior

Local translation of nuclear-encoded mitochondrial mRNAs is essential for mitochondrial activity, yet there is little insight into the role that axonal trafficking of these transcripts play in neuronal function and behavior. Previously, we identified a 38 nucleotide stem-loop structure (zipcode) in...

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Detalhes bibliográficos
Main Authors: Kar, Amar N., Sun, Ching-Yu, Reichard, Kathryn, Gervasi, Noreen M., Pickel, James, Nakazawa, Kazu, Gioio, Anthony E., Kaplan, Barry B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133933/
https://ncbi.nlm.nih.gov/pubmed/24151253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.22141
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