Low-dose radiation activates Nrf1/2 through reactive species and the Ca(2+)/ERK1/2 signaling pathway in human skin fibroblast cells

In the current study, we explored the effect of LDR on the activation of Nrfs transcription factor involved in cellular redox events. Experiments were carried out utilizing 0.05 and 0.5 Gy X-ray irradiated normal human skin fibroblast HS27 cells. The results showed LDR induced Nrf1 and Nrf2 activati...

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Библиографические подробности
Главные авторы: Lee, Eun Kyeong, Kim, Jin-Ah, Park, Seong Joon, Kim, Jeung Ki, Heo, Kyu, Yang, Kwang Mo, Son, Tae Gen
Формат: Artigo
Язык:Inglês
Опубликовано: Korean Society for Biochemistry and Molecular Biology 2013
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Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133890/
https://ncbi.nlm.nih.gov/pubmed/23710636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2013.46.5.199
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