Phloroglucinol Attenuates Ultraviolet B-Induced 8-Oxoguanine Formation in Human HaCaT Keratinocytes through Akt and Erk-Mediated Nrf2/Ogg1 Signaling Pathways

Ultraviolet B (UVB) radiation causes DNA base modifications. One of these changes leads to the generation of 8-oxoguanine (8-oxoG) due to oxidative stress. In human skin, this modification may induce sunburn, inflammation, and aging and may ultimately result in cancer. We investigated whether phloro...

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Bibliografske podrobnosti
izdano v:Biomol Ther (Seoul)
Main Authors: Piao, Mei Jing, Kim, Ki Cheon, Kang, Kyoung Ah, Fernando, Pincha Devage Sameera Madushan, Herath, Herath Mudiyanselage Udari Lakmini, Hyun, Jin Won
Format: Artigo
Jezik:Inglês
Izdano: The Korean Society of Applied Pharmacology 2021
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7771840/
https://ncbi.nlm.nih.gov/pubmed/32587122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2020.059
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