Nrf2-Heme oxygenase-1 modulates autophagy and inhibits apoptosis triggered by elevated glucose levels in renal tubule cells

BACKGROUND: Autophagy is a highly balanced process in which lysosomes remove aged and damaged organelles and cellular proteins. Autophagy is essential to maintain homeostasis in the kidneys. METHODS: Using human renal tubule cells HK-2, we assessed the impact of high glucose (HG) on autophagy. We al...

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Bibliografski detalji
Izdano u:Kidney Res Clin Pract
Glavni autori: Kim, Joo-Heon, Kim, Kyeong Min, Jeong, Jin Uk, Shin, Jong Ho, Shin, Jae Min, Bang, Ki Tae
Format: Artigo
Jezik:Inglês
Izdano: Korean Society of Nephrology 2019
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727894/
https://ncbi.nlm.nih.gov/pubmed/31067610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.23876/j.krcp.18.0152
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