ANTIBODY MEDIATED IMMUNOTHERAPY OF MACAQUES CHRONICALLY INFECTED WITH SHIV SUPPRESSES VIREMIA

Neutralizing antibodies (NAbs) can confer immunity to primate lentiviruses by blocking infection in macaque models of AIDS(1–4). However, earlier studies of anti-HIV 1 NAbs administered to infected individuals or humanized mice, reported poor control of virus replication and the rapid emergence of r...

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Main Authors: Shingai, Masashi, Nishimura, Yoshiaki, Klein, Florian, Mouquet, Hugo, Donau, Olivia K., Plishka, Ronald, Buckler-White, Alicia, Piatak, Michael, Lifson, Jeffrey D., Dimitrov, Dimiter, Nussenzweig, Michel C., Martin, Malcolm A.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133787/
https://ncbi.nlm.nih.gov/pubmed/24172896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12746
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