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The distribution of genomic variations in human iPSCs is related to replication timing reorganization during reprogramming

Cell fate change involves significant genome reorganization, including change in replication timing, but how these changes are related to genetic variation has not been examined. To study how change in replication timing that occurs during reprogramming impacts the copy number variation (CNV) landsc...

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Detalhes bibliográficos
Main Authors: Lu, Junjie, Li, Hu, Hu, Ming, Sasaki, Takayo, Baccei, Anna, Gilber, David M., Liu, Jun S., Collins, James J., Lerou, Paul H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133748/
https://ncbi.nlm.nih.gov/pubmed/24685138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.007
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