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General rules for the arrangements and gating motions of pore-lining helices in homomeric ion channels
The pore-lining helix (PLH) bundles are central to the function of all ion channels, as their conformational rearrangements dictate channel gating. Here we explore all plausible oligomeric arrangements of the PLH bundles within homomeric ion channels by building models using generic restraints. In p...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133698/ https://ncbi.nlm.nih.gov/pubmed/25105557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5641 |
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