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General rules for the arrangements and gating motions of pore-lining helices in homomeric ion channels
The pore-lining helix (PLH) bundles are central to the function of all ion channels, as their conformational rearrangements dictate channel gating. Here we explore all plausible oligomeric arrangements of the PLH bundles within homomeric ion channels by building models using generic restraints. In p...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133698/ https://ncbi.nlm.nih.gov/pubmed/25105557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5641 |
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