Role of macrophage sialoadhesin in host defense against the sialylated pathogen group B Streptococcus

ABSTRACT: Several bacterial pathogens decorate their surfaces with sialic acid (Sia) residues within cell wall components or capsular exopolysaccharides. Sialic acid expression can promote bacterial virulence by blocking complement activation or by engagement of inhibitory sialic acid-binding immuno...

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Bibliographic Details
Main Authors: Chang, Yung-Chi, Olson, Joshua, Louie, Aaron, Crocker, Paul R., Varki, Ajit, Nizet, Victor
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133643/
https://ncbi.nlm.nih.gov/pubmed/24788876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-014-1157-y
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