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Role of macrophage sialoadhesin in host defense against the sialylated pathogen group B Streptococcus

ABSTRACT: Several bacterial pathogens decorate their surfaces with sialic acid (Sia) residues within cell wall components or capsular exopolysaccharides. Sialic acid expression can promote bacterial virulence by blocking complement activation or by engagement of inhibitory sialic acid-binding immuno...

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Main Authors: Chang, Yung-Chi, Olson, Joshua, Louie, Aaron, Crocker, Paul R., Varki, Ajit, Nizet, Victor
格式: Artigo
語言:Inglês
出版: Springer Berlin Heidelberg 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133643/
https://ncbi.nlm.nih.gov/pubmed/24788876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-014-1157-y
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