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Role of macrophage sialoadhesin in host defense against the sialylated pathogen group B Streptococcus

ABSTRACT: Several bacterial pathogens decorate their surfaces with sialic acid (Sia) residues within cell wall components or capsular exopolysaccharides. Sialic acid expression can promote bacterial virulence by blocking complement activation or by engagement of inhibitory sialic acid-binding immuno...

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Détails bibliographiques
Auteurs principaux: Chang, Yung-Chi, Olson, Joshua, Louie, Aaron, Crocker, Paul R., Varki, Ajit, Nizet, Victor
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133643/
https://ncbi.nlm.nih.gov/pubmed/24788876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-014-1157-y
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