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Glucocorticoid receptor coordinates transcription factor-dominated regulatory network in macrophages

BACKGROUND: Inflammation triggered by infection or injury is tightly controlled by glucocorticoid hormones which signal via a dedicated transcription factor, the Glucocorticoid Receptor (GR), to regulate hundreds of genes. However, the hierarchy of transcriptional responses to GR activation and the...

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Библиографические подробности
Главные авторы: Chinenov, Yurii, Coppo, Maddalena, Gupte, Rebecca, Sacta, Maria A, Rogatsky, Inez
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133603/
https://ncbi.nlm.nih.gov/pubmed/25099603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-656
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