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P53 inhibition exacerbates late-stage anthracycline cardiotoxicity
AIMS: Doxorubicin (DOX) is an effective anti-cancer therapeutic, but is associated with both acute and late-stage cardiotoxicity. Children are particularly sensitive to DOX-induced heart failure. Here, the impact of p53 inhibition on acute vs. late-stage DOX cardiotoxicity was examined in a juvenile...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133592/ https://ncbi.nlm.nih.gov/pubmed/24812279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu118 |
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