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Targeted expression of cyclin D2 ameliorates late stage anthracycline cardiotoxicity

AIMS: Doxorubicin (DOX) is a widely used and effective anti-cancer therapeutic. DOX treatment is associated with both acute and late onset cardiotoxicity, limiting its overall efficacy. Here, the impact of cardiomyocyte cell cycle activation was examined in a juvenile model featuring aspects of acut...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Zhu, Wuqiang, Reuter, Sean, Field, Loren J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452322/
https://ncbi.nlm.nih.gov/pubmed/30423020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy273
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