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Developmental Treatment with Ethinyl Estradiol, but Not Bisphenol A, Causes Alterations in Sexually Dimorphic Behaviors in Male and Female Sprague Dawley Rats

The developing central nervous system may be particularly sensitive to bisphenol A (BPA)-induced alterations. Here, pregnant Sprague Dawley rats (n = 11–12/group) were gavaged daily with vehicle, 2.5 or 25.0 μg/kg BPA, or 5.0 or 10.0 μg/kg ethinyl estradiol (EE(2)) on gestational days 6–21. The BPA...

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Autors principals: Ferguson, Sherry A., Law, Charles Delbert, Kissling, Grace E.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133561/
https://ncbi.nlm.nih.gov/pubmed/24798382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu077
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