Overlapping but distinct effects of genistein and ethinyl estradiol (EE(2)) in female Sprague-Dawley rats in multigenerational reproductive and chronic toxicity studies

Genistein and ethinyl estradiol (EE(2)) were examined in multigenerational reproductive and chronic toxicity studies that had different treatment intervals among generations. Sprague-Dawley rats received genistein (0, 5, 100, or 500 ppm) or EE(2) (0, 2, 10, or 50 ppb) in a low phytoestrogen diet. No...

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Hauptverfasser: Delclos, K. Barry, Weis, Constance C., Bucci, Thomas J., Olson, Greg, Mellick, Paul, Sadovova, Natalya, Latendresse, John R., Thorn, Brett, Newbold, Retha R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706590/
https://ncbi.nlm.nih.gov/pubmed/19159674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2008.12.005
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