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Novel insights related to CF neutrophils

In this issue of Blood, Pohl et al demonstrate that neutrophils from patients with mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR) have impaired exocytosis of gelatinase and specific granules, altered ion homeostasis resulting in deactivation of the small GTPase Rab2...

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Bibliografski detalji
Glavni autor: Uriarte, Silvia M.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133497/
https://ncbi.nlm.nih.gov/pubmed/25124777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-583831
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