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Novel insights related to CF neutrophils
In this issue of Blood, Pohl et al demonstrate that neutrophils from patients with mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR) have impaired exocytosis of gelatinase and specific granules, altered ion homeostasis resulting in deactivation of the small GTPase Rab2...
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| Hlavní autor: | |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133497/ https://ncbi.nlm.nih.gov/pubmed/25124777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-583831 |
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