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Novel insights related to CF neutrophils

In this issue of Blood, Pohl et al demonstrate that neutrophils from patients with mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR) have impaired exocytosis of gelatinase and specific granules, altered ion homeostasis resulting in deactivation of the small GTPase Rab2...

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Autor principal: Uriarte, Silvia M.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133497/
https://ncbi.nlm.nih.gov/pubmed/25124777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-583831
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