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Increased Generation of HIV-1 gp120-Reactive CD8(+) T Cells by a DNA Vaccine Construct Encoding the Chemokine CCL3

DNA vaccines based on subunits from pathogens have several advantages over other vaccine strategies. DNA vaccines can easily be modified, they show good safety profiles, are stable and inexpensive to produce, and the immune response can be focused to the antigen of interest. However, the immunogenic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Øynebråten, Inger, Hinkula, Jorma, Fredriksen, Agnete B., Bogen, Bjarne
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133255/
https://ncbi.nlm.nih.gov/pubmed/25122197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104814
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