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Targeted DNA vaccines for enhanced induction of idiotype-specific B and T cells
Background: Idiotypes (Id) are antigenic determinants localized in variable (V) regions of Ig. Id-specific T and B cells (antibodies) play a role in immunotherapy of Id(+) tumors. However, vaccine strategies that enhance Id-specific responses are needed. Methods: Id(+) single-chain fragment variable...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483591/ https://ncbi.nlm.nih.gov/pubmed/23115759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00154 |
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