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Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules

Lipid antigens are presented to T cells by the non-polymorphic MHC class I-related CD1 molecules. Microsomal triglyceride transfer protein (MTP) is an endoplasmic reticulum (ER)-resident chaperone that has been shown to lipidate the group 2 CD1 molecule CD1d and thus to regulate its function. We now...

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Detalhes bibliográficos
Main Authors: Kaser, Arthur, Hava, David L., Dougan, Stephanie K., Chen, Zhangguo, Zeissig, Sebastian, Brenner, Michael B., Blumberg, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132950/
https://ncbi.nlm.nih.gov/pubmed/18624350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200738102
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