CD1d-mediated Presentation of Endogenous Lipid Antigens by Adipocytes Requires Microsomal Triglyceride Transfer Protein

Obesity-induced adipose tissue (AT) dysfunction results in a chronic low-grade inflammation that predisposes to the development of insulin resistance and type 2 diabetes. During the development of obesity, the AT-resident immune cell profile alters to create a pro-inflammatory state. Very recently,...

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Detalhes bibliográficos
Main Authors: Rakhshandehroo, Maryam, Gijzel, Sanne M. W., Siersbæk, Rasmus, Broekema, Marjoleine F., de Haar, Colin, Schipper, Henk S., Boes, Marianne, Mandrup, Susanne, Kalkhoven, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139226/
https://ncbi.nlm.nih.gov/pubmed/24966328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.551242
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