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Loss of both phospholipid and triglyceride transfer activities of microsomal triglyceride transfer protein in abetalipoproteinemia

Mutations in microsomal triglyceride transfer protein (MTP) cause abetalipoproteinemia (ABL), characterized by the absence of plasma apoB-containing lipoproteins. In this study, we characterized the effects of various MTP missense mutations found in ABL patients with respect to their expression, sub...

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Detalhes bibliográficos
Main Authors: Khatun, Irani, Walsh, Meghan T., Hussain, M. Mahmood
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646455/
https://ncbi.nlm.nih.gov/pubmed/23475612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M031658
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