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A short motif in Kir6.1 consisting of 4 phosphorylation repeats underlies the vascular K(ATP) channel inhibition by protein kinase C

Vascular ATP-sensitive K(+) channels are inhibited by multiple vasoconstricting hormones via the PKC pathway. However, the molecular substrates for PKC phosphorylation remain unknown. To identify the PKC sites, Kir6.1/SUR2B and Kir6.2/SUR2B were expressed in HEK293 cells. Following channel activatio...

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Detalhes bibliográficos
Main Authors: Shi, Yun, Cui, Ningren, Shi, Weiwei, Jiang, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132833/
https://ncbi.nlm.nih.gov/pubmed/18048350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708769200
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