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A short motif in Kir6.1 consisting of 4 phosphorylation repeats underlies the vascular K(ATP) channel inhibition by protein kinase C
Vascular ATP-sensitive K(+) channels are inhibited by multiple vasoconstricting hormones via the PKC pathway. However, the molecular substrates for PKC phosphorylation remain unknown. To identify the PKC sites, Kir6.1/SUR2B and Kir6.2/SUR2B were expressed in HEK293 cells. Following channel activatio...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4132833/ https://ncbi.nlm.nih.gov/pubmed/18048350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708769200 |
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